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Safety Information
 

Monitoring Your CLL Symptoms

Tell your doctor or nurse if you notice any symptoms or a sudden change in your health. Below, are possible signs that your CLL has advanced. But only your doctor can tell if these symptoms are related to your CLL. And because you may not have symptoms, be sure to visit your doctor regularly. Your doctor will closely monitor your condition. You, too, can be involved by monitoring symptoms.

Download or print the Symptom Checklist below and keep it handy while you’re monitoring your symptoms. If you have any symptoms, be sure to talk to your doctor about them. Also, be sure to ask any questions you have about your treatment.

 
 

Monitor your symptoms

Talking openly and directly about symptoms can help you and your doctor manage your CLL.

   

Your symptom checklist

While your doctor watches for:

  • An increase in the number of CLL cells
  • A decrease in the number of normal blood cells
  • Swelling in the lymph nodes, liver, or spleen

You should watch for:

  • Swollen lymph nodes in the neck, armpit, or groin. This swelling can be painless
  • Discomfort or a feeling of fullness in the abdomen
  • Feeling very tired or weak
  • Feeling short of breath
  • Fever, night sweats, or weight loss
  • Infections of the skin or body

Even if you do not have symptoms, be sure to visit your doctor regularly.

 
 

Keep in mind: You may have heard the term watch-and-wait. That means the doctor and patient will watch the CLL for symptoms and not start treatment unless needed. Some people with CLL never need treatment.

This information does not take the place of talking with your doctor. Discuss with your doctor any questions you have about your medical condition or your treatment.

Next Section Infusion Day Checklist

Indications

RITUXAN® (Rituximab) is indicated in combination with fludarabine and cyclophosphamide (FC chemotherapy) for the treatment of patients with:

  • Previously untreated CD20-positive CLL
  • Previously treated CD20-positive CLL

People with serious infections should not receive RITUXAN.

Safety Information

  • RITUXAN can cause serious side effects that can lead to death, including: infusion reactions, tumor lysis syndrome (TLS; kidney failure due to fast breakdown of cancer cells), severe skin and mouth reactions, and progressive multifocal leukoencephalopathy (PML; a rare, serious brain infection).
  • RITUXAN has also been associated with serious and life-threatening side effects, including: the return of active hepatitis B virus infection with sudden and serious liver problems including liver failure, and death, other serious infections that can lead to death, heart problems, kidney problems, and stomach and serious bowel problems including blockage and tears in the bowel that can sometimes lead to death.
  • The most common side effects of RITUXAN seen in clinical trials of patients with CLL were infusion reactions and low white blood cells, which can increase the risk of infections. Before starting treatment with RITUXAN it is important for you to talk to your doctor about your medical history.
  • Tell your doctor about any side effect that bothers you or that does not go away. These are not all of the possible side effects with RITUXAN. For more information, ask your doctor.

Please see full Prescribing Information, including Medication Guide, in PDF format.