Important Safety Information
Signs and Symptoms of Non-Hodgkin’s Lymphoma
A swollen lymph node in the neck
You may or may not have signs and symptoms of non-Hodgkin’s lymphoma (NHL). If you do, they may appear suddenly. Or they may show up over time. Possible non-Hodgkin’s lymphoma signs and symptoms include:
- Swelling in lymph nodes, often in the neck, armpit, or groin. This swelling can be painless
- Fever, night sweats, and weight loss. Oncologists refer to these general symptoms as “B symptoms” because they are not related to the location of the cancer
- Feeling very tired and weak
Signs and symptoms may result from many different illnesses. So medical tests are needed to diagnose and determine the type and stage of NHL. On the next page, you’ll learn about the different tests used to diagnose non-Hodgkin’s lymphoma.
This information does not take the place of talking with your doctor. Discuss with your doctor any questions you have about your medical condition or your treatment.
Indications and Important Safety Information
RITUXAN® (Rituximab) is indicated for the treatment of patients with:
- Relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL as a single agent
- Previously untreated follicular, CD20-positive, B-cell NHL in combination with CVP chemotherapy
- Non-progressing (including stable disease), low-grade, CD20-positive, B-cell NHL, as a single agent, after first-line CVP chemotherapy
- Previously untreated diffuse large B-cell, CD20-positive NHL in combination with CHOP or other anthracycline-based chemotherapy regimens
People with serious infections should not receive RITUXAN.
Important Safety Information:
- RITUXAN can cause serious side effects that can lead to death, including: infusion reactions, tumor lysis syndrome (TLS; kidney failure due to fast breakdown of cancer cells), severe skin and mouth reactions, and progressive multifocal leukoencephalopathy (PML; a rare, serious brain infection).
- RITUXAN has also been associated with serious and life-threatening side effects, including: the return of active hepatitis B virus infection with sudden and serious liver problems including liver failure, and death, other serious infections that can lead to death, heart problems, kidney problems, and stomach and serious bowel problems including blockage and tears in the bowel that can sometimes lead to death.
- The most common side effects of RITUXAN seen in patients with non-Hodgkin’s lymphoma were infusion reactions, fever, chills, low white blood cells, infections, body aches, and tiredness. Before starting treatment with RITUXAN it is important to talk to your doctor about your medical history.
- Tell your doctor about any side effect that bothers you or that does not go away. These are not all of the possible side effects with RITUXAN. For more information, ask your doctor
Please see full Prescribing Information, including Medication Guide.
