Rituxan Rituximab

RITUXAN® for Aggressive Non-Hodgkin's Lymphoma (NHL)RITUXAN for Aggressive Non-Hodgkin's Lymphoma (NHL)

 

How RITUXAN Can Help Improve Survival Rates in DLBCL (Aggressive Non-Hodgkin's Lymphoma)

RITUXAN® plus CHOP chemotherapy has been shown in clinical studies to significantly prolong survival for many patients with diffuse large B-cell lymphoma (DLBCL). DLBCL is the most common type of aggressive NHL (high-grade or fast-growing NHL). In a large clinical study known as GELA LNH 98-5, 69% of patients receiving RITUXAN plus CHOP chemotherapy were surviving at 2 years versus 58% of those receiving CHOP chemotherapy alone. RITUXAN was also studied in 2 other large clinical trials known as E4494 and MInT. Explore this section to learn more about:

 

Initial Treatment

INDICATIONS

RITUXAN® (rituximab) is indicated for the treatment of patients with:

  • Relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL as a single agent
  • Previously untreated follicular, CD20-positive, B-cell NHL in combination with CVP chemotherapy
  • Non-progressing (including stable disease), low-grade, CD20-positive B-cell NHL, as a single agent, after first-line CVP chemotherapy
  • Previously untreated diffuse large B-cell, CD20-positive NHL in combination with CHOP or other anthracycline-based chemotherapy regimens

IMPORTANT SAFETY INFORMATION

RITUXAN can cause serious side effects, some of which can be life-threatening, including: Progressive Multifocal Leukoencephalopathy (PML), infusion reactions, Tumor Lysis Syndrome (TLS), and severe skin reactions. Other serious and life-threatening side effects with RITUXAN include: hepatitis B virus reactivation, heart problems, infections, and stomach and bowel problems. Common side effects during RITUXAN infusions include: fever, headache, chills and shakes, nausea, itching, hives, cough, sneezing, and throat irritation or tightness.

Tell your doctor about any side effects that bother you or that do not go away. These are not all of the possible side effects with RITUXAN. Ask your doctor for more information.

Please read the Medication Guide in HTML or PDF versions for more information.