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Need answers to RA questions?

Call the RISE Support Line toll-free at
1-877-4-RITUXAN
(1-877-474-8892)
Mon-Fri 8am-11pm EST or Sat 9am-1pm EST

Learn More
 

Need reimbursement information?

Call Genentech Access Solutions toll-free at
1-877-4RITUXAN
(1-877-474-8892), then press 2
Mon-Fri 9am - 8pm EST

Visit Genentech AccessSolutions.com

Need answers to questions about Rituxan?

Call the RISE Support Line toll-free at
1-877-4-RITUXAN
(1-877-474-8892)
Then press 3 / 2 / 2
Mon-Fri 8am-11pm EST or Sat 9am-1pm EST

 

Need reimbursement information?

Call Genentech Access Solutions toll-free at
1-877-4RITUXAN
(1-877-474-8892), then press 2
Mon-Fri 9am - 8pm EST

Visit Genentech AccessSolutions.com

Video on Rituximab (RITUXAN) and its MOA

Roles of B Cells in RA and the MOA of RITUXAN

Watch an informational video explaining how RITUXAN works in RA.

Watch Video
 

INDICATION
Rituxan (Rituximab) in combination with methotrexate is indicated to reduce signs and symptoms and slows the progression of structural damage in adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response to one or more TNF antagonist therapies.

 

Important Safety Information
Boxed WARNINGS

Fatal Infusion Reactions: Rituxan administration can result in serious, including fatal infusion reactions. Deaths within 24 hours of RITUXAN infusion have occurred. Approximately 80% of fatal infusion reactions occurred in association with the first infusion.

Tumor Lysis Syndrome (TLS): Acute renal failure requiring dialysis with instances of fatal outcome can occur in the setting of TLS following treatment of non-Hodgkin’s lymphoma (NHL) patients with RITUXAN.

Severe Mucocutaneous Reactions: Severe, including fatal, mucocutaneous reactions, can occur in patients receiving RITUXAN.

Progressive Multifocal Leukoencephalopathy (PML): JC virus infection resulting in PML and death can occur in patients treated with Rituxan.

Please see full prescribing information, including Boxed WARNINGS.

REFERENCES

  1. Weinblatt ME et al. N Engl J Med. 1999;340:253-259.
  2. Maini R et al. Lancet. 1999;354:1932-1939.
  3. Weinblatt ME et al. Arthritis Rheum. 2003;48:35-45.
  4. Keystone EC et al. Arthritis Rheum. 2004;50:1400-1411.
  5. Data on file, Genentech/Biogen Idec