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WHAT IS RITUXAN?

Rituxan is a prescription medicine used in adults with another medicine called methotrexate to reduce the signs and symptoms of moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a tumor necrosis factor (TNF) antagonist has been used and did not work well.

People with serious infections should not receive Rituxan.

IMPORTANT SAFETY INFORMATION

Rituxan therapy can result in serious side effects, some which can be life-threatening. These include infusion reactions, tumor lysis syndrome (TLS), severe mucocutaneous reactions, and progressive multifocal leukoencephalopathy (PML). Other serious, potentially life threatening side effects are: hepatitis B infection that may become active again, serious infections, heart problems and low blood cell counts.

Common side effects include infections and infusion reactions.

Before treatment with Rituxan, patients should tell their doctor if they have an infection, including one that will not go away or keeps coming back.

If patients experience any symptoms or side effects during or after Rituxan treatment, they should seek immediate medical attention.

For additional important safety information please see the Rituxan full Prescribing Information, including BOXED WARNINGS and Medication Guide.

Print About Rituxan

While many people respond well to anti-TNF therapies, a significant number of people with rheumatoid arthritis (RA) may not. Fortunately, advances in RA research have led to a different type of RA treatment—a treatment that may work when anti-TNFs have either stopped working well or not worked well at all. It's called Rituxan® (rituximab).

  • With just 1 course of 2 infusions, Rituxan is the only treatment for rheumatoid arthritis (RA) that can provide 6 months of relief by improving pain and symptoms. Plus, it can protect joints by slowing the damage of RA. So if Rituxan works well for you, you won't have to miss out on the things that matter.
    • In studies, more than half of the people taking Rituxan experienced a clinically significant improvement in RA signs and symptoms (ACR 20 response). Individual results may vary. Please ask your doctor for more information.
  • For people who haven't responded well to one or more anti-TNFs, Rituxan is the first and only treatment proven to protect joints by slowing the damage of RA.
  • Although Rituxan works differently from other RA treatments, it has been tested extensively. In fact, Rituxan has more than 10 years of clinical experience across all approved uses and over 1,000,000 patient exposures.
  • Keep in mind that not everyone responds to Rituxan in the same way, and some people have experienced side effects during or after their treatment with Rituxan. For more information, be sure to review the Rituxan Medication Guide and talk with your doctor.
  • Side effects information: Common side effects associated with Rituxan include infusion reactions and infections.

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