Before you start exploring, take the time to read the side effect information.Roll over to read more
WHAT DOES RITUXAN TREAT?
Rheumatoid arthritis (RA): with another prescription medicine called methotrexate, to reduce the signs and symptoms of moderate to severe active RA in adults, after treatment with at least one other medicine called a tumor necrosis factor (TNF) antagonist has been used and did not work well enough.
People with serious infections should not receive Rituxan. It is not known if Rituxan is safe or effective in children.
IMPORTANT SIDE EFFECT INFORMATION
What is the most important information I should know about Rituxan?Rituxan can cause serious side effects that can lead to death, including:
Infusion reactions: infusion reactions are the most common side effect of Rituxan treatment. Serious infusion reactions can happen during your infusion or within 24 hours after your infusion of Rituxan. Your doctor should give you medicines before your infusion of Rituxan to decrease your chance of having a severe infusion reactionTell your doctor or get medical help right away if you get any of these symptoms during or after an infusion of Rituxan:
- Hives (red itchy welts) or rash
- Swelling of your lips, tongue, throat, or face
- Sudden cough
- Shortness of breath, difficulty breathing, or wheezing
- Dizziness or feeling faint
- Palpitations (feeling like your heart is racing or fluttering)
- Chest pain
Severe skin and mouth reactions: tell your doctor or get medical help right away if you get any of these symptoms at any time during your treatment with Rituxan:
- Painful sores or ulcers on your skin, lips, or in your mouth
- Peeling skin
- Hepatitis B virus (HBV) reactivation: before Rituxan treatment, your doctor will do blood tests to check for HBV infection. If you have had hepatitis B or are a carrier of hepatitis B virus, receiving Rituxan could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems, including liver failure and death. You should not receive Rituxan if you have active hepatitis B liver disease. Your doctor will monitor you for hepatitis B infection during and for several months after you stop receiving Rituxan
Progressive multifocal leukoencephalopathy (PML): PML is a rare, serious brain infection caused by a virus. People with weakened immune systems can get PML. Your chance of getting PML may be higher if you are treated with Rituxan alone or with other medicines that weaken your immune system. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PMLTell your doctor right away if you have any of the following symptoms or if anyone close to you notices these symptoms:
- Confusion or problems thinking
- Loss of balance
- Change in the way you walk or talk
- Decreased strength or weakness on one side of your body
- Blurred vision or loss of vision
What should I tell my doctor before receiving Rituxan?Before receiving Rituxan, tell your doctor if you:
- Have had a severe infusion reaction to Rituxan in the past
- Have a history of heart problems, irregular heartbeat, chest pain, or lung or kidney problems
- Have had an infection, currently have an infection, or have a weakened immune system
- Have had a recent vaccination or are scheduled to receive vaccinations
- Are pregnant or planning to become pregnant. Talk to your doctor about effective birth control
- Are breast-feeding or plan to breast-feed
- Are taking any medications, including prescription and nonprescription medicines, vitamins, and herbal supplements
What are the possible side effects of Rituxan?Rituxan can cause serious and life-threatening side effects, including:
Tumor lysis syndrome (TLS): TLS is caused by the fast breakdown of cancer cells. TLS can cause you to have:
- Kidney failure and the need for dialysis treatment
- Abnormal heart rhythm
Serious infections: serious infections can happen during and after treatment with Rituxan, and can lead to death. Rituxan can lower the ability of your immune system to fight infections. Types of serious infections that can happen with Rituxan include bacterial, fungal, and viral infections. After receiving Rituxan, some patients have developed low levels of certain antibodies in their blood for a long period of time (longer than 11 months). Some of these patients with low antibody levels developed infections. Call your doctor right away if you have any symptoms of infection:
- Cold symptoms, such as runny nose or sore throat that do not go away
- Flu symptoms, such as cough, tiredness, and body aches
- Earache or headache
- Pain during urination
- White patches in the mouth or throat
- Cuts, scrapes, or incisions that are red, warm, swollen, or painful
- Heart problems: Rituxan may cause chest pain and irregular heartbeat, which may need treatment, or your doctor may decide to stop your treatment with Rituxan
- Kidney problems: especially if you are receiving Rituxan for NHL. Your doctor should do blood tests to check how well your kidneys are working
- Stomach and serious bowel problems that can sometimes lead to death: bowel problems, including blockage or tears in the bowel can happen if you receive Rituxan with chemotherapy medicines to treat non-Hodgkin’s lymphoma. Tell your doctor right away if you have any stomach area pain during treatment with Rituxan
Low blood cell counts: your doctor may do blood tests during treatment with Rituxan to check your blood cell counts
- White blood cells: white blood cells fight against bacterial infections. Low white blood cells can cause you to get infections, which may be serious
- Red blood cells: red blood cells carry oxygen to your body tissues and organs
- Platelets: platelets are blood cells that help your blood to clot
What are common side effects during treatment with Rituxan?
- Infusion reactions
- Body aches
- Low white blood cell count
Other side effects include:
- Aching joints during or within hours of receiving an infusion
- More frequent upper respiratory tract infections
How will I receive Rituxan?
- Rituxan is given by infusion through a needle placed in a vein (intravenous infusion) in your arm. Talk to your doctor about how you will receive Rituxan
- Your doctor may prescribe medicines before each infusion of Rituxan to reduce side effects of infusions such as fever and chills
- Your doctor should do regular blood tests to check for side effects of Rituxan
Before each Rituxan treatment, your doctor or nurse will ask you questions about your general health. Tell your doctor or nurse about any new symptoms.
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.
Please see the Rituxan Medication Guide including most serious side effects for additional important side effect information.
- What personally identifiable information of yours we may collect from you through our website
- How we may use your personally identifiable information
- Limits on how we would share and disclose your personally identifiable information
- Our policy regarding links to third party websites
- Security of our website
- How you can correct and update your personally identifiable information
Please note that Genentech and Biogen Idec websites are directed towards users who reside in the United States of America. It is not our intent to gather personally identifiable information from individuals residing outside the U.S.
Information Collection and Use
You can generally visit our website without revealing any personally identifiable information about yourself. However, to access certain options and services we may ask you to provide certain personally identifiable information and without providing such personally identifiable information, you may be unable to access certain options and services. We (along with our third party partners engaged to provide marketing and advertising on our behalf) collect personally identifiable information about you only if you voluntarily provide it to us and you have the option not to provide any personally identifiable information to us. The following is personally identifiable information that you may voluntarily provide to us and how we use it:
- Surveys. Information obtained from you on web surveys, such as contact information (name and shipping address), demographic information (zip code, age level) and medical condition. We may use this personally identifiable information to provide you with information and services for which you have expressed an interest or that you may find useful based on your answers in a survey. Additionally, we may refer to your personally identifiable information to better understand your needs and how we can improve our website.
- Newsletters. Information obtained from your request to subscribe to a newsletter, such as contact information (name and e-mail address). We may use this personally identifiable information to deliver the newsletters that you have elected to receive.
- Registration. Information obtained from you on registration forms used to process your requests for services and information, such as contact information (name, address, e-mail address), password, username or code, age, date of birth, gender, ethnicity and medical condition. This registration information may also be gathered if you register for certain services via fax or mail. We may use this information to send you a welcoming e-mail to verify your username and password, website updates, special offers, notices regarding relevant medical conditions and treatment, or other information responsive to the data that you provide to us. Additionally, we may refer to your personally identifiable information to better understand your needs and how we can improve our website.
- Email Content to a Friend. Information obtained from you regarding friend or family name and e-mail address, if you elect to use our referral service for sending some of our website content to friends and family. This personally identifiable information will be used to automatically send the friend or family member an e-mail from you inviting them to visit the website. We may store this information for the sole purpose of sending this one-time e-mail.
Genentech and Biogen Idec are the owners of all information collected on this website. In addition to the purposes described above, any information we collect may also be used for analytics purposes (e.g., evaluating site usage patterns, assessing throughput) so that we can gauge the effectiveness of our programs and improve the usefulness of information presented to users.
Our websites are not intended for or designed to attract children under the age of 13. Moreover, we do not knowingly collect any personally identifiable information from anyone under the age of 18 without the consent of a parent or guardian, and you must be 18 years of age or older to submit registration or survey information. Should you believe that a minor of whom you are a parent or guardian has registered, please contact us at firstname.lastname@example.org and we will make reasonable efforts to remove all personally identifiable information related to the minor.
Cookies and GIF files
Some of our websites may use cookie technology to identify users who have previously visited so the user is recognized upon return, thereby saving them time while on our website. A cookie is a piece of data stored on the user’s hard drive containing information about the user. Usage of a cookie is in no way linked to any personally identifiable information while on our website. If a user rejects the cookie, they may still use our website. A cookie may be placed by us, or by vendors or service agencies who work with us or with our partners.
This website and emails we send to you may contain transparent GIF files (also known as “web beacons,” “action tags,” or “pixel tags”) to help manage online advertising. These GIF files are used by us and our ad management partners to recognize when a visitor views a web page or opens an email. This information enables us to learn which emails and advertisements bring users to our website. The information collected and shared with our ad management partners through the use of GIF files is anonymous and is not personally identifiable.
Log Files and Aggregate Information
We may track the total number of visitors to our website, the number of visitors to each page of our website, IP addresses, and the domain names of our users' Internet Service Providers, and we may analyze these data for trends and statistics in the aggregate, but such information will be in aggregate form only and it will not contain personally identifiable data. Such aggregate information is not linked to any personally identifiable information that can identify any individual person.
We may use such aggregate information to analyze trends, administer the website, track users’ movement, and gather broad demographic information for aggregate use. We may share this aggregate information with our corporate partners and contracted vendors to assist us in operating the website and to enable them to better understand Genentech’s and Biogen Idec’s businesses.
Sharing and Disclosure
Links to Third Party Sites
Genentech, Biogen Idec, and their third party providers may employ procedural and technological security measures, consistent with industry practice. Such measures are reasonably designed to protect your personally identifiable information from loss, unauthorized access, disclosure, alteration or destruction. Genentech and Biogen Idec may use encryption, password protection, secure socket layers, internal restrictions and other security measures to help prevent unauthorized access to your personally identifiable information.
Correction/Updating Personally Identifiable Information
Genentech and Biogen Idec are committed to respecting your right to access and correct your personal information. You can call us at 877-GENENTECH and we will be happy to assist you with your request.
You may also “opt-out" of receiving e-mails and other communications from us by using the unsubscribe feature included in the e-mails we send.
Contacting Genentech and Biogen Idec
Attn: Privacy Office
1 DNA Way
South San Francisco, CA 94080
- Added section ‘Contacting Genentech and Biogen Idec’