IMPORTANT SAFETY INFORMATION
Rituxan can result in serious side effects, some of which could be life threatening. These include:
- infusion reactions
- tumor lysis syndrome (TLS)
- severe skin and mouth reactions
- progressive multifocal leukoencephalopathy (PML)
Other serious, potentially life-threatening side effects are:
- hepatitis B infection that may become active again
- serious infections
- heart problems
- low blood cell counts
Common side effects include infections and infusion reactions. Before treatment with Rituxan, patients should tell their doctor if they have an infection, including one that will not go away or that keeps coming back. If patients experience any symptoms or side effects during or after Rituxan treatment, they should seek immediate medical attention. These are not all of the possible side effects with Rituxan. Tell your doctor about any side effect that bothers you or that does not go away.
Please read the Rituxan full Prescribing Information, including the Medication Guide. If you have any questions about this information, be sure to discuss them with your doctor.
WHAT IS RITUXAN?
Rituxan® (rituximab) is a prescription medicine used in adults with another prescription medicine called methotrexate, to reduce the signs and symptoms of moderate to severe active RA, after at least one other medicine called a tumor necrosis factor (TNF) inhibitor has been used and did not work well enough.

