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IMPORTANT SAFETY INFORMATION

Rituxan can result in serious side effects, some of which could be life threatening. These include:

  • infusion reactions
  • tumor lysis syndrome (TLS)
  • severe skin and mouth reactions
  • progressive multifocal leukoencephalopathy (PML)

Other serious, potentially life-threatening side effects are:

  • hepatitis B infection that may become active again
  • serious infections
  • heart problems
  • low blood cell counts

Common side effects include infections and infusion reactions. Before treatment with Rituxan, patients should tell their doctor if they have an infection, including one that will not go away or that keeps coming back. If patients experience any symptoms or side effects during or after Rituxan treatment, they should seek immediate medical attention. These are not all of the possible side effects with Rituxan. Tell your doctor about any side effect that bothers you or that does not go away.

Please read the Rituxan full Prescribing Information, including the Medication Guide. If you have any questions about this information, be sure to discuss them with your doctor.

WHAT IS RITUXAN?

Rituxan® (rituximab) is a prescription medicine used in adults with another prescription medicine called methotrexate, to reduce the signs and symptoms of moderate to severe active RA, after at least one other medicine called a tumor necrosis factor (TNF) inhibitor has been used and did not work well enough.

Looking forward to results

As you begin your Rituxan® (rituximab) treatment, you may be wondering how soon to expect results and how long they will last. In clinical trials, people were treated with Rituxan and methotrexate or methotrexate alone. They also received glucocorticoids. At the time of their first check-up - just 2 weeks after treatment - many of them had seen a significant improvement in their symptoms. Of those patients treated with Rituxan and methotrexate, many saw that same improvement last through 6 months.

Up to 6 months of symptom improvement

Rituxan is the only treatment for rheumatoid arthritis (RA) that provides up to 6 months of symptom improvement from just 1 course of treatment (2 infusions), and can also help protect joints for the long-term by continuing to slow the damage of RA. And the benefits don't stop there. Studies have shown that if you continue to take Rituxan, it can continue to provide that same symptom improvement.

Be mindful of potential side effects

Keep in mind that Rituxan may increase your risk of infection, and people with serious infections should not receive Rituxan. So tell your doctor if you experience a nagging cough, fever, chills, congestion, or any flu-like symptoms.