Chronic Lymphocytic Leukemia

Signs and symptoms of CLL

Everyone experiences CLL differently. It does not always cause symptoms. And in early stages of CLL, you are less likely to be bothered by symptoms.

Still, CLL is a serious disease. And it is important to pay attention to how CLL may be affecting you. Tell your doctor if you notice any symptoms or changes in your health.

The signs and symptoms you should watch for include:

  • Weakness
  • Feeling tired
  • Feeling short of breath
  • Weight loss
  • Fever
  • Night sweats
  • Enlarged lymph nodes (felt as lumps under the skin)
  • Pain or a sense of "fullness" in the belly (especially after eating a small meal)
  • Infections
  • Excess bruising and bleeding

Other things can cause symptoms of CLL. Only your doctor will be able to tell if your symptoms are related to CLL.

Your doctor will be looking for:

  • An increase in the number of abnormal white blood cells
  • A decrease in the number of normal blood cells
  • Swelling in your lymph nodes, liver, or spleen

Worsening of symptoms may be a reason to start treatment for CLL. Remember to talk with your healthcare team about your symptoms.


RITUXAN is available by prescription only.