Pemphigus vulgaris is a rare type of blistering skin disease.
B-cells produce antibodies. It is thought that people with PV have B-cells that create specific antibodies that target the proteins that glue cells together.
Normally, antibodies fight germs. But, if you have PV, they can also cause lesions or blisters on your skin. Areas like the inside of your mouth can also be affected.
The body makes a kind of glue to hold skin cells together. This also occurs in places like the inside of the mouth.
The specific antibodies found in people with PV attack the glue and cause it to break down. The skin cells then separate from each other, causing lesions or blisters.
Rituxan is a biologic medicine that targets special types of B-cells. Your doctor may prescribe it for moderate to severe PV.
A biologic medicine is a type of medication that is developed using biological processes, which are similar to what happens in your body naturally. These treatments can be used to target certain parts of your immune system and to fight certain diseases, such as PV.
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