If you are not being helped enough by an anti-TNF, you and your doctor may want to make a change. Consider some of the potential benefits and risks of switching to Rituxan plus methotrexate (MTX).
A key clinical study known as the REFLEX Trial showed that at 6 months:
Rituxan can cause serious side effects that can lead to death, including:
Please see the Important Side Effect Information page and the Rituxan Prescribing Information and Medication Guide for additional Important Side Effect Information, including Most Serious Side Effects.
In the REFLEX Trial, Rituxan plus MTX was proven to slow joint damage for many patients (60%) during the first year of treatment compared to placebo plus MTX (46%).
ACR, American College of Rheumatology; RA, rheumatoid arthritis; TNF, tumor necrosis factor.
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